Average Cost of PGD: Is Preimplantation Genetic Diagnosis Worth It?

When couples undergo IVF treatment, one of the most important considerations is the health of their future child. That’s where Preimplantation Genetic Diagnosis (PGD) comes in. PGD is a specialised procedure that allows doctors to test embryos for genetic or chromosomal abnormalities before they are transferred to the womb. For couples at risk of passing on inherited conditions, PGD offers reassurance and a higher chance of having a healthy baby.

But alongside the medical benefits, many couples ask: How much does PGD cost? And is the investment really worth it? Let’s break it down.

What Is PGD and How Does It Work?

PGD, or Preimplantation Genetic Diagnosis, is an advanced technique used during IVF. After embryos are created in the lab through fertilisation, a few cells are carefully removed from each embryo. These cells are then analysed to check for specific genetic disorders or chromosomal abnormalities. Only embryos free of the targeted condition are selected for transfer to the uterus.

PGD is often recommended for:

• Couples with a known family history of genetic diseases.
  
• Women of advanced maternal age.
• Couples who have faced recurrent miscarriages.
• Patients who have had repeated IVF failures.

It’s worth noting that PGD is sometimes confused with PGS (Preimplantation Genetic Screening). While PGS checks for overall chromosomal health, PGD is focused on detecting specific inherited conditions.

Average Cost of PGD in India and Worldwide

The cost of PGD varies significantly across countries and clinics.

• In India: The cost of PGD generally ranges between ₹2.5 lakhs and ₹5 lakhs. This is in addition to the cost of IVF treatment.
• In the US/UK: The cost is much higher, typically around $4,000 to $7,500 per cycle, again excluding the basic IVF expenses.

Why does the price vary so much?

1. Number of embryos tested – More embryos tested means higher lab costs.
2. Technology used – Advanced methods like Next Generation Sequencing (NGS) are more expensive but also more accurate.
3. Clinic reputation and lab expertise – Leading fertility clinics may charge more due to higher success rates.

The critical thing to remember is that PGD is never a standalone cost. It is always an add-on to IVF, which means couples should be prepared for the combined expense.

What Is Included in the PGD Cost?

When you pay for PGD, you’re not just paying for a single test. The fee usually covers:

• Embryo biopsy – The delicate process of extracting a few cells from the embryo.
• Genetic testing in the lab – Advanced screening for targeted disorders or chromosomal issues.
• Embryo freezing and storage – While testing is ongoing, embryos are safely frozen.
• Transfer of selected embryos – Only healthy embryos are transferred back into the uterus.
• Specialist consultations – Genetic counselling and expert guidance throughout the process.

Factors That Influence PGD Cost

Several elements determine the final bill for PGD testing:

1. Clinic location and reputation – Top-tier clinics with advanced technology and higher success rates may charge more.
2. Type of genetic test required – Testing for a single-gene disorder is different from a broader chromosomal scan.
3. Number of embryos tested – Costs rise with each additional embryo that undergoes biopsy.
4. Need for frozen embryo thawing – If embryos are already frozen, they may need to be thawed for testing, adding extra charges.
5. Additional IVF procedures – Techniques like ICSI (Intracytoplasmic Sperm Injection) or extended embryo culture may increase overall costs.

Is PGD Worth the Cost?

This is the question every couple grapples with. Here’s how to weigh the value:

Benefits of PGD:

• Peace of mind – Knowing your child is free of specific genetic conditions.
• Higher success rates – Healthy embryos increase the chances of a successful pregnancy.
• Reduced risk of miscarriage – Since chromosomal abnormalities are a leading cause of miscarriages, PGD helps lower this risk.
• Long-term savings – Preventing the birth of a child with a serious genetic condition may save families from the emotional and financial burden of lifelong treatments and hospital care.

When PGD Might Not Be Necessary:

• Couples with no family history of genetic diseases.
• Young couples with strong fertility health and no recurrent miscarriages.
• Situations where IVF is being done for reasons unrelated to genetic risks.

Ultimately, whether PGD is “worth it” depends on your personal circumstances. For some, it is an essential part of family planning. For others, it may not be medically required.

In Conclusion

The cost of PGD in India typically ranges from ₹2.5 lakhs to ₹5 lakhs, while international clinics may charge $4,000–$7,500 per cycle. While this can feel like a significant expense, many couples find that the peace of mind, reduced miscarriage risk, and higher chance of a healthy pregnancy outweigh the financial burden. At the end of the day, the decision comes down to your medical needs, emotional readiness, and financial situation. The best way forward is to consult with a trusted fertility expert who can guide you based on your unique case.

Take the Next Step with Expert Guidance

Deciding whether PGD is right for you can feel overwhelming, but you don’t have to make the decision alone. With over 25 years of expertise in IVF, embryology, and genetic testing, Goral Gandhi provides compassionate, personalised guidance. Book your consultation today and take the first confident step toward building your healthy family and future.

FAQs

1. Can PGD be done on frozen embryos?
Yes. PGD can be performed on previously frozen embryos. The embryos are thawed, biopsied for testing, and then refrozen or transferred once results are ready.

2. How much does PGD testing cost in India?
In India, PGD testing usually costs between ₹2.5 lakhs and ₹5 lakhs, depending on the clinic, number of embryos tested, and type of genetic analysis.

3. Is PGD included in IVF treatment costs?
No. PGD is an additional procedure performed alongside IVF. The cost of PGD is separate and always added to the standard IVF charges.

4. What is the difference between PGD and PGS?
PGD (Preimplantation Genetic Diagnosis) is used to detect specific genetic diseases, while PGS (Preimplantation Genetic Screening) checks for overall chromosomal health in embryos.

5. Is PGD worth the cost for every couple?
PGD is most valuable for couples at risk of passing on genetic disorders, women of advanced maternal age, or those with recurrent miscarriages. Couples without these risks may not always require PGD.